[脱氧核糖核酸酶I在实验性白血病发展中的可能作用]
[Possible role of DNAse I in the development of experimental leukemia].
作者信息
Drozhennikov V A, Perevezentseva O S, Orlova E B
出版信息
Biull Eksp Biol Med. 1979 Oct;88(10):439-41.
PMID:497383
Abstract
An increase in the DNAase 1 activity in the serum and an increase in the DNAase inhibitor activity in the spleen in the development of virus Friend leukemia were demonstrated. Increased activity of the inhibitor in the spleen was also revealed after intravenous injection of exogenous DNAase 1 into mice. A potential role of serum DNAase 1 in the development of experimental leukemia is discussed.
摘要
在Friend病毒白血病发展过程中，血清中脱氧核糖核酸酶1（DNAase 1）活性增加，脾脏中脱氧核糖核酸酶抑制剂活性增加。给小鼠静脉注射外源性DNAase 1后，脾脏中抑制剂的活性也有所增加。本文讨论了血清DNAase 1在实验性白血病发展中的潜在作用。
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