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分离出一种参与人体对淋球菌感染免疫反应的淋病奈瑟菌抗原。

Isolation of an antigen of Neisseria gonorrhoeae involved in the human immune response to gonococcal infection.

作者信息

Schmale J D, Danielsson D G, Smith J F, Lee L, Peacock W L

出版信息

J Bacteriol. 1969 Aug;99(2):469-71. doi: 10.1128/jb.99.2.469-471.1969.

Abstract

Ion-exchange chromatography was used to isolate a fraction from disrupted gonococci which reacts with sera from patients with gonococcal disease in complement-fixation and gel-diffusion tests. This antigenic fraction was shown to be the same as that previously described as having been isolated by gel filtration. The method reported here has the advantage of greater rapidity of isolation together with some improvement in purity.

摘要

离子交换色谱法用于从破碎的淋球菌中分离出一种组分,该组分在补体结合试验和凝胶扩散试验中能与淋病患者的血清发生反应。已证明这种抗原性组分与先前描述的通过凝胶过滤分离得到的组分相同。本文报道的方法具有分离速度更快以及纯度有所提高的优点。

相似文献

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Studies on circulating gonococcal antibodies and antigens.
Can J Microbiol. 1978 Feb;24(2):109-11. doi: 10.1139/m78-020.

引用本文的文献

1
Particulate Fractions of Neisseria gonorrhoeae.淋病奈瑟菌的颗粒部分。
Infect Immun. 1971 Apr;3(4):624-32. doi: 10.1128/iai.3.4.624-632.1971.

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