淋病奈瑟菌两种选定抗原的反应性。
Reactivity of two selected antigens of Neisseria gonorrhoeae.
作者信息
Reising G, Schmale J D, Danielsson D G, Thayer J D
出版信息
Appl Microbiol. 1969 Sep;18(3):337-9. doi: 10.1128/am.18.3.337-339.1969.
Two antigen preparations, the soluble antigen and a fraction 1 thereof, isolated in the course of a systematic study of the various antigens of the virulent gonococcus, have been investigated for their ability to serve as antigens for the detection of antibody in patients infected with the gonococcus. The soluble antigen was reactive with 88.2% of the sera from infected females, and fraction 1 was reactive with 71.6% of the sera. Of sera from infected males, only 27.6% reacted with the soluble antigen and only 20.4% with fraction 1. Of sera from individuals presumed free of gonococcal infection, approximately 4% reacted with the soluble antigen; none reacted with fraction 1. This study suggests that these antigens might be adaptable to the detection of human gonococcal antibody, especially in the female.
在对强毒力淋球菌的各种抗原进行系统研究过程中分离出的两种抗原制剂，即可溶性抗原及其1号组分，已对其作为检测淋球菌感染患者抗体的抗原的能力进行了研究。可溶性抗原与88.2%的感染女性血清发生反应，1号组分与71.6%的血清发生反应。在感染男性的血清中，只有27.6%与可溶性抗原发生反应，只有20.4%与1号组分发生反应。在假定未感染淋球菌的个体血清中，约4%与可溶性抗原发生反应；无一与1号组分发生反应。这项研究表明，这些抗原可能适用于检测人淋球菌抗体，尤其是在女性中。
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