Zaslavsky B Y, Borovskaya A A, Lisichkin A Y, Davidovich Y A, Rogozhin S V
Chem Phys Lipids. 1979 Jun-Jul;24(3):297-303. doi: 10.1016/0009-3084(79)90035-5.
The lytic action of a number of N-acyl amino acids on lecithin liposomes was examined. The agents' affinity for lecithin liposome membrane was measured and the results obtained were treated to estimate the interactions of the amino acid residues with the lecithin polar head group at the surface of the liposome membrane. The data were considered in relation to the study of the surfactant effects on the erythrocyte volume. The ability of the suggested approach to obtain information on protein-lipid interactions inaccessible by other techniques is briefly commented on.
研究了多种N-酰基氨基酸对卵磷脂脂质体的裂解作用。测定了这些试剂对卵磷脂脂质体膜的亲和力，并对所得结果进行处理，以评估氨基酸残基与脂质体膜表面卵磷脂极性头部基团的相互作用。结合表面活性剂对红细胞体积影响的研究对这些数据进行了考量。简要评述了所提出的方法获取其他技术无法获得的蛋白质-脂质相互作用信息的能力。
