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Thyopac-3检测在甲状腺功能体外评估中的应用评价

Evaluation of Thyopac-3 test in the in-vitro assessment of thyroid function.

作者信息

Clark F, Brown H J

出版信息

Br Med J. 1970 Mar 21;1(5698):713-5. doi: 10.1136/bmj.1.5698.713.

Abstract

Thyopac-3, a new commercial test kit for the in-vitro assessment of thyroid function, has been appraised in a group of 411 patients. The Thyopac-3 test was found to be simple and rapid to perform and accurate in diagnosis. Of 117 patients shown to be euthyroid by other criteria, 5% had Thyopac-3 values outside the normal range (derived from a group of 135 normal patients), and 10 of 79 thyrotoxic and 4 of 37 hypothyroid patients had values within the normal range.In a direct comparison in 190 patients with the resin uptake test the Thyopac-3 test emerged very favourably in regard to diagnostic accuracy and was technically easier and quicker to carry out. There was a non-linear negative correlation between results from the two procedures.

摘要

Thyopac-3是一种用于体外评估甲状腺功能的新型商用检测试剂盒,已在411名患者中进行了评估。结果发现,Thyopac-3检测操作简单、快速,诊断准确。在117名经其他标准判定为甲状腺功能正常的患者中,5%的患者Thyopac-3值超出正常范围(该范围源自135名正常患者),79名甲状腺功能亢进患者中有10名以及37名甲状腺功能减退患者中有4名的检测值在正常范围内。在190名患者中与树脂摄取试验进行直接比较时,Thyopac-3检测在诊断准确性方面表现出色,并且在技术上更简便、执行更快。两种检测方法的结果之间存在非线性负相关。

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