Lal S, Modawal K K, Fowle A S, Peach B, Popham R D
Br Med J. 1970 Aug 1;3(5717):256-7. doi: 10.1136/bmj.3.5717.256.
Four patients with acute brucellosis are described, none of whom had any connexion with farming or milk industry, the source of infection being different in each case. The diagnosis was made by serological tests, and in three of the four cases was confirmed by positive cultures from bone marrow (one case) and liver biopsy (two cases). Treatment with the combination of trimethoprim/sulphamethoxazole was successful in three out of four cases, and in the fourth case failure may have been due to the development of trimethoprim resistance.
本文描述了4例急性布鲁氏菌病患者，他们均与农业或乳制品行业无任何关联，且每例患者的感染源各不相同。通过血清学检测做出诊断，4例中的3例经骨髓培养阳性（1例）和肝活检培养阳性（2例）得以确诊。4例患者中有3例采用甲氧苄啶/磺胺甲恶唑联合治疗取得成功，第4例治疗失败可能是由于对甲氧苄啶产生了耐药性。
