Jeroudi M O, Halim M A, Harder E J, Al-Siba'i M B, Ziady G, Mercer E N
Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Br Heart J. 1987 Sep;58(3):279-83. doi: 10.1136/hrt.58.3.279.
Brucella endocarditis is an underdiagnosed, fatal complication of human brucellosis. Four successfully treated cases of Brucella endocarditis are reported. The development of a new valvar lesion and bulky vegetations seen on echocardiography helped to identify Brucella endocarditis occurring during systemic brucellosis. The aortic valve was affected in all four patients, and in one the mitral valve was also affected. Medical treatment did not cure the patients and all needed valve replacement--for haemodynamic deterioration in three and because a further embolism was feared in one. Antibiotics were continued for six to nine months after operation. There was no early or late mortality and no recurrence after a follow up of 15 months.
布鲁氏菌性心内膜炎是人类布鲁氏菌病一种诊断不足的致命并发症。本文报告了4例成功治疗的布鲁氏菌性心内膜炎病例。超声心动图上出现的新瓣膜病变和大量赘生物有助于识别系统性布鲁氏菌病期间发生的布鲁氏菌性心内膜炎。4例患者的主动脉瓣均受累，其中1例二尖瓣也受累。药物治疗未能治愈患者，所有患者均需要进行瓣膜置换——3例因血流动力学恶化，1例因担心再次发生栓塞。术后继续使用抗生素6至9个月。随访15个月后，无早期或晚期死亡病例，也无复发。
