人血清β脂蛋白中的亚基异质性。
Subunit heterogeneity in human serum beta lipoprotein.
作者信息
Kane J P, Richards E G, Havel R J
出版信息
Proc Natl Acad Sci U S A. 1970 Aug;66(4):1075-82. doi: 10.1073/pnas.66.4.1075.
Abstract
The apoprotein of human serum beta lipoprotein has been prepared in a lipid-free and soluble form by a technique of interfacial extraction in the presence of guanidinium hydrochloride and nonionic amphiphile. Gel permeation chromatography of maleylated apobeta lipoprotein separates two protein fractions with different amino acid compositions. The smaller particle has a molecular weight of 2.6 x 10(4).
摘要
通过在盐酸胍和非离子两亲物存在下的界面萃取技术，制备出了无脂质且可溶形式的人血清β脂蛋白载脂蛋白。马来酰化载脂蛋白β脂蛋白的凝胶渗透色谱法分离出了两种具有不同氨基酸组成的蛋白质组分。较小的颗粒分子量为2.6×10⁴。
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