Rohrmann G F, Krueger R G
J Virol. 1970 Sep;6(3):269-79. doi: 10.1128/JVI.6.3.269-279.1970.
H (heavy) and L (light) MS-2 particles differ in density, absorption spectrum, and infectivity. Studies on their sedimentation, ribonucleic acid (RNA) content and infectivity, appearance under the electron microscope, ribonuclease sensitivity, and A-protein content failed to demonstrate any difference between the two particle types. Studies on the size, RNA content, and density of the capsid and two smaller coat protein components were also conducted. The antigenic relatedness of five different viral and subviral particles of MS-2 were studied by using immunodiffusion and neutralization. Capsids and the H and L viral particles were shown to be antigenically related, whereas the coat protein monomers and dimers were shown to be unrelated to the higher-molecular-weight particles.
重（H）型和轻（L）型MS - 2颗粒在密度、吸收光谱和感染性方面存在差异。对它们的沉降、核糖核酸（RNA）含量与感染性、电子显微镜下的外观、核糖核酸酶敏感性以及A蛋白含量的研究未能证明这两种颗粒类型之间存在任何差异。还对衣壳以及两种较小的衣壳蛋白成分的大小、RNA含量和密度进行了研究。通过免疫扩散和中和试验研究了MS - 2的五种不同病毒和亚病毒颗粒的抗原相关性。结果表明，衣壳以及H型和L型病毒颗粒具有抗原相关性，而衣壳蛋白单体和二聚体与高分子量颗粒无关。
