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本文引用的文献

1
Deoxyribonucleic Acid of the blue-green algae (cyanophyta).蓝藻（蓝藻门）的脱氧核糖核酸
Bacteriol Rev. 1967 Dec;31(4):315-31. doi: 10.1128/br.31.4.315-331.1967.
2
Photoreactivation of UV-irradiated blue-green algal virus LPP-1.紫外线照射的蓝藻病毒LPP-1的光复活作用
Virology. 1967 Apr;31(4):657-64. doi: 10.1016/0042-6822(67)90194-8.
3
Comparison of blue-green algae virus LPP-1 and the morphologically related viruses G-3 and coliphage T7.蓝绿藻病毒LPP - 1与形态相关病毒G - 3及大肠杆菌噬菌体T7的比较
Virology. 1968 Apr;34(4):675-8. doi: 10.1016/0042-6822(68)90088-3.
4
The structural gene for a T7 endonuclease essential for phage DNA synthesis.噬菌体DNA合成所必需的一种T7核酸内切酶的结构基因。
Proc Natl Acad Sci U S A. 1970 Jan;65(1):242-8. doi: 10.1073/pnas.65.1.242.
5
LPP-1 infection of the blue-green alga Plectonema boryanum. 3. Protein synthesis.蓝绿藻鞘丝藻的LPP - 1感染。3. 蛋白质合成。
J Virol. 1970 Dec;6(6):841-6. doi: 10.1128/JVI.6.6.841-846.1970.
6
LPP-1 infection of the blue-green alga Plectonema boryanum. I. Electron microscopy.蓝绿藻鞘丝藻的LPP - 1感染。I. 电子显微镜观察
J Virol. 1970 Dec;6(6):820-33. doi: 10.1128/JVI.6.6.820-833.1970.
7
Morphology of a virus of blue-green algae and properties of its deoxyribonucleic acid.蓝绿藻病毒的形态及其脱氧核糖核酸的性质
J Virol. 1967 Apr;1(2):344-61. doi: 10.1128/JVI.1.2.344-361.1967.

蓝绿藻鞘丝藻的LPP - 1感染。II. 病毒脱氧核糖核酸合成与宿主脱氧核糖核酸分解

LPP-1 infection of the blue-green alga Plectonema boryanum. II. Viral deoxyribonucleic acid synthesis and host deoxyribonucleic acid breakdown.

作者信息

Sherman L A, Haselkorn R

出版信息

J Virol. 1970 Dec;6(6):834-40. doi: 10.1128/JVI.6.6.834-840.1970.

DOI:10.1128/JVI.6.6.834-840.1970
PMID:4992999
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC376201/
Abstract

Host and viral deoxyribonucleic acid (DNA) metabolism in LPP-1-infected Plectonema boryanum was studied by equilibrium centrifugation in CsCl gradients. Approximately 50% of the host DNA is degraded to acid-soluble material between 3 and 7 hr after infection. Most of the acid-soluble product is reincorporated into viral DNA. Incorporation of exogenous (3)H-adenine into viral DNA can be detected very early after infection (within the first 2 hr), but the bulk of viral DNA synthesis occurs between 6 and 8 hr. Both the breakdown of host DNA and the synthesis of viral DNA require protein synthesis during the first few hours of infection.

摘要

通过在氯化铯梯度中进行平衡离心，研究了感染LPP - 1的鞘丝藻中宿主和病毒脱氧核糖核酸（DNA）的代谢情况。感染后3至7小时内，约50%的宿主DNA被降解为酸溶性物质。大部分酸溶性产物重新掺入病毒DNA中。感染后很早就能检测到外源（3）H - 腺嘌呤掺入病毒DNA（在最初2小时内），但大部分病毒DNA合成发生在6至8小时之间。在感染的最初几个小时内，宿主DNA的分解和病毒DNA的合成均需要蛋白质合成。