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Oxidation of synephrine by type A and type B monoamine oxidase.

作者信息

Suzuki O, Matsumoto T, Oya M, Katsumata Y

出版信息

Experientia. 1979 Oct 15;35(10):1283-4. doi: 10.1007/BF01963957.

DOI:10.1007/BF01963957
PMID:499398
Abstract

Synephrine (SP) was found to be a substrate for monoamine oxidase (MAO) in rat brain mitochondria, showing the Km and Vmax values of 250 microM and 32.6 nmoles/mg of protein/30 min respectively. The inhibition studies showed that the SP oxidation was carried out by both type A and type B MAO and a major part of the activity was due to type A MAO.

摘要

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Molecules. 2023 Apr 29;28(9):3813. doi: 10.3390/molecules28093813.
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Single-Dose Pharmacokinetics and Metabolism of the Oral Decongestant Phenylephrine HCl in Children and Adolescents.口服减充血剂盐酸去氧肾上腺素在儿童和青少年中的单剂量药代动力学及代谢
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Potential Herb-Drug Interactions in the Management of Age-Related Cognitive Dysfunction.年龄相关性认知功能障碍管理中的潜在草药-药物相互作用。
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Interaction of p-synephrine on the pharmacodynamics and pharmacokinetics of gliclazide in animal models.对羟基福林对格列齐特在动物模型中的药效学和药代动力学的影响
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Some observations upon a new inhibitor of monoamine oxidase in brain tissue.关于一种脑组织中单胺氧化酶新抑制剂的一些观察结果。
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6
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