Il'iuchenok T Iu, Frigidova L M, Shadurskiĭ K S, Lepekhin V P, Ignatova L A
Farmakol Toksikol. 1979 Nov-Dec;42(6):643-7.
Toxicity and radioprotective properties of 18 derivatives of oxazine and thiazine with a varying degree of the cycle saturation were studied in experiments on mice. Monotypic regularity in variations of their toxic properties relative to the chemical structure was noted. 4,4,6-Trimethyl-2-dimethylamino-4H-1,3-oxazine exerted a pronounced radioprotective action.
在对小鼠进行的实验中,研究了18种具有不同程度环饱和度的恶嗪和噻嗪衍生物的毒性及辐射防护特性。注意到它们的毒性特性相对于化学结构的变化存在单型规律性。4,4,6-三甲基-2-二甲基氨基-4H-1,3-恶嗪具有显著的辐射防护作用。