半乳糖血症：结构基因突变的证据。
Galactosemia: evidence for a structural gene mutation.
作者信息
Tedesco T A, Mellman W J
出版信息
Science. 1971 May 14;172(3984):727-8. doi: 10.1126/science.172.3984.727.
PMID:4995463
Abstract
Identical immunoprecipitin reactions appeared in double immunodiffusion between rabbit anltibodies to human galactose-1-phosphate uridyl transferase and red cell preparations from both normal and galactosemic individuals. The galactosemic erythrocyte preparations quantitatively absorbed the antiboy that immunoprecipitates enzymatically active galactose-1-phosphate uridyl transferase.
摘要
在兔抗人半乳糖-1-磷酸尿苷酰转移酶抗体与正常人和半乳糖血症患者的红细胞制剂之间的双向免疫扩散中，出现了相同的免疫沉淀反应。半乳糖血症红细胞制剂定量吸收了能使具有酶活性的半乳糖-1-磷酸尿苷酰转移酶发生免疫沉淀的抗体。
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