Lin F H, Thormar H
J Virol. 1971 May;7(5):582-7. doi: 10.1128/JVI.7.5.582-587.1971.
A single-stranded ribonucleic acid(s) has been isolated from purified virions of visna virus. It consists of two major components, namely 63S and "4S," under the conditions employed for ribonucleic acid (RNA) extraction. The 63S component can be converted to subunits by heat and dimethylsulfoxide treatments. Analyses by base composition indicate that the "4S" RNA isolated from visna virus is not a random breakdown product of the 63S component as a result of extraction, nor is it randomly derived from cellular RNA.
已从纯化的维斯纳病毒颗粒中分离出一种单链核糖核酸。在用于核糖核酸(RNA)提取的条件下,它由两个主要成分组成,即63S和“4S”。63S成分可通过加热和二甲基亚砜处理转化为亚基。碱基组成分析表明,从维斯纳病毒中分离出的“4S”RNA既不是提取过程中63S成分的随机降解产物,也不是随机来源于细胞RNA。