梅迪病核酸的特性以及病毒粒子中依赖核糖核酸和脱氧核糖核酸的脱氧核糖核酸聚合酶的存在。
Properties of maedi nucleic acid and the presence of ribonucleic acid- and deoxyribonucleic acid-dependent deoxyribonucleic acid polymerase in the virions.
作者信息
Lin F H, Thormar H
出版信息
J Virol. 1972 Aug;10(2):228-33. doi: 10.1128/JVI.10.2.228-233.1972.
Abstract
Maedi virus contains a ribonucleic acid (RNA) which can be resolved into three major components, namely, 62S, 33S, and 13S, by sucrose gradient centrifugation. The presence of RNA- and deoxyribonucleic acid (DNA)-dependent DNA polymerase in virions of maedi virus was demonstrated. The enzyme product could be converted into acid-soluble form by pancreatic deoxyribonuclease, but was resistant to digestion by pancreatic ribonuclease and to hydrolysis by NaOH.
摘要
梅迪病毒含有一种核糖核酸（RNA），通过蔗糖梯度离心可将其分解为三个主要成分，即62S、33S和13S。已证实梅迪病毒的病毒粒子中存在RNA依赖性和脱氧核糖核酸（DNA）依赖性DNA聚合酶。该酶产物可被胰脱氧核糖核酸酶转化为酸溶性形式，但对胰核糖核酸酶的消化和NaOH的水解具有抗性。
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本文引用的文献
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Maedi, a chronic, progressive infection of sheep's lungs.梅迪病，一种绵羊肺部的慢性进行性感染。
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