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1
Prick-tests and serological tests in the diagnosis of allergic reactivity to enzymes used in washing products.用于诊断对洗涤产品中所用酶的过敏反应的点刺试验和血清学试验。
Br J Ind Med. 1971 Jul;28(3):303-7. doi: 10.1136/oem.28.3.303.
2
[Occupational asthma due to proteases in the detergent industry].
Schweiz Med Wochenschr. 1969 Nov 1;99(44):1584-6.
3
Enzyme sensitisation in consumers of enzyme-containing washing powder.含酶洗衣粉消费者中的酶致敏反应。
Lancet. 1970 Dec 5;2(7684):1153-7. doi: 10.1016/s0140-6736(70)90340-5.
4
Characterization of induced homocytotropic antibody to ragweed and timothy pollen in non-atopic dogs.非特应性犬体内针对豚草和梯牧草花粉的诱导亲细胞性抗体的特性研究
Clin Exp Immunol. 1971 May;8(5):825-34.
5
Biological effects of proteolytic enzyme detergents.蛋白水解酶洗涤剂的生物学效应。
Thorax. 1976 Dec;31(6):621-34. doi: 10.1136/thx.31.6.621.
6
Allergic bronchial reactions to inhalation of enzymes of Bacillus subtilis.吸入枯草芽孢杆菌酶引起的变应性支气管反应。
Am Rev Respir Dis. 1973 Mar;107(3):387-94. doi: 10.1164/arrd.1973.107.3.387.
7
[Demonstration of reaginic (Ige) and precipitating (IgG) antibodies in the serum of a patient allergic to Bacillus subtilis enzymes].
Rev Eur Etud Clin Biol. 1972 Feb;17(2):204-8.
8
Sensitivity to enzyme additives in laundry detergent workers.洗衣洗涤剂工人对酶添加剂的敏感性。
J Allergy Clin Immunol. 1971 Nov;48(5):262-6. doi: 10.1016/0091-6749(71)90026-1.
9
[Clinical and immunological effect of washing powder enzymes on workers and users (author's transl)].洗衣粉酶对工人和使用者的临床及免疫学影响（作者译）
Allerg Immunol (Leipz). 1977;23(3):185-92.
10
Detergent enzymes--a new challenge for the respiratory tract.洗涤剂酶——对呼吸道的新挑战。
Rev Roum Med Intern. 1974;11(2):185-90.

引用本文的文献

1
Lung function, atopy, specific hypersensitivity, and smoking of workers in the enzyme detergent industry over 11 years.酶洗涤剂行业工人11年的肺功能、特应性、特异性超敏反应及吸烟情况
Br J Ind Med. 1985 Jan;42(1):43-50. doi: 10.1136/oem.42.1.43.
2
Clinical and immunological responses to occupational exposure to alpha-amylase in the baking industry.烘焙行业中职业性接触α-淀粉酶的临床和免疫反应。
Br J Ind Med. 1991 Sep;48(9):604-8. doi: 10.1136/oem.48.9.604.
3
Biological effects of proteolytic enzyme detergents.蛋白水解酶洗涤剂的生物学效应。
Thorax. 1976 Dec;31(6):621-34. doi: 10.1136/thx.31.6.621.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
The adsorption of proteins on erythrocytes treated with tannic acid and subsequent hemagglutination by antiprotein sera.蛋白质在经单宁酸处理的红细胞上的吸附以及随后抗蛋白质血清引起的血细胞凝集。
J Exp Med. 1951 Feb;93(2):107-20. doi: 10.1084/jem.93.2.107.
3
A simple chromatographic method for preparation of gamma globulin.一种制备γ球蛋白的简易色谱法。
Proc Soc Exp Biol Med. 1960 Jan;103:250-2. doi: 10.3181/00379727-103-25476.
4
Hypersensitivity to purified trypsin and chymotrypsin.对纯化胰蛋白酶和胰凝乳蛋白酶过敏。
N Engl J Med. 1961 Aug 17;265:332-4. doi: 10.1056/NEJM196108172650708.
5
Allergy to chymotrypsin.
J Allergy. 1957 Jan;28(1):89-90. doi: 10.1016/0021-8707(57)90074-6.
6
Survey of workers exposed to dusts containing derivatives of Bacillus subtilis.对接触含有枯草芽孢杆菌衍生物粉尘的工人进行的调查。
Br Med J. 1970 Jun 13;2(5710):629-33. doi: 10.1136/bmj.2.5710.629.
7
[Occupational asthma due to proteases in the detergent industry].
Schweiz Med Wochenschr. 1969 Nov 1;99(44):1584-6.
8
Antitrypsin deficiency in chronic obstructive lung disease.慢性阻塞性肺疾病中的抗胰蛋白酶缺乏症
Lancet. 1970 Apr 25;1(7652):891-2. doi: 10.1016/s0140-6736(70)91714-9.
9
An epidemiological study of workers producing enzyme washing powders.一项关于生产酶洗衣粉工人的流行病学研究。
Lancet. 1970 Apr 4;1(7649):689-93. doi: 10.1016/s0140-6736(70)90924-4.
10
Allergic reactions of the lungs to enzymes of Bacillus subtilis.肺部对枯草芽孢杆菌酶的过敏反应。
Lancet. 1969 Jun 14;1(7607):1181-4. doi: 10.1016/s0140-6736(69)92166-7.

用于诊断对洗涤产品中所用酶的过敏反应的点刺试验和血清学试验。

Prick-tests and serological tests in the diagnosis of allergic reactivity to enzymes used in washing products.

作者信息

How M J, Cambridge G W

出版信息

Br J Ind Med. 1971 Jul;28(3):303-7. doi: 10.1136/oem.28.3.303.

DOI:10.1136/oem.28.3.303
PMID:4997564
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1069506/
Abstract

303-307. Standardized prick-test antigens for use in the detection of allergic reactivity to enzymes (Alcalase and Maxatase) used in washing products have been prepared. These materials contained all the potentially allergenic components of the crude enzyme preparations. Tests showed that these materials were more appropriate, as prick-test antigens, than the crystalline enzyme. The presence of reagin-mediated, immediate-type allergy in factory workers was confirmed by prick-tests and passive transfer tests. Sera from these subjects and controls contained enzyme-specific haemagglutinating antibody and gave precipitin-like reactions with solutions of Alcalase and Maxatase. The latter reaction involved serum components electrophoretically similar to, or identical with, α-globulins.

摘要

303 - 307. 已制备出用于检测对洗涤产品中使用的酶（碱性蛋白酶和嗜热菌蛋白酶）过敏反应的标准化点刺试验抗原。这些材料包含粗酶制剂中所有潜在的过敏原成分。试验表明，作为点刺试验抗原，这些材料比结晶酶更合适。通过点刺试验和被动转移试验证实了工厂工人中存在反应素介导的速发型过敏。这些受试者和对照组的血清含有酶特异性血凝抗体，并与碱性蛋白酶和嗜热菌蛋白酶溶液发生沉淀样反应。后一种反应涉及电泳上与α球蛋白相似或相同的血清成分。