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血吸虫病的化学预防剂：14,15-环氧香叶基香叶醇。

Chemoprophylactic agent in schistosomiasis: 14,15-epoxygeranylgeraniol.

作者信息

Mors W B, dos Santos Filho M F, Monteiro H J, Gilbert B, Pellegrino J

出版信息

Science. 1967 Aug 25;157(3791):950-1. doi: 10.1126/science.157.3791.950.

DOI:10.1126/science.157.3791.950
PMID:5006418
Abstract

The occurrence of all-trans (-)-14,15-epoxygeranyl-geraniol in Pterodon pubescens Benth. is established, and its prophylactic activity against infection by Schitsosma mansoni demonstrated. Two other diterpenes present in the oil are inactive.

摘要

已证实毛瓣翼豆（Pterodon pubescens Benth.）中存在全反式（-）-14,15-环氧香叶基香叶醇，并证明了其对曼氏血吸虫感染的预防活性。该油中存在的另外两种二萜没有活性。

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Science. 1967 Aug 25;157(3791):950-1. doi: 10.1126/science.157.3791.950.
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