上皮样组织细胞含量高的恶性淋巴瘤。

Hayes D, Robertson J H

J Clin Pathol. 1979 Jul;32(7):675-80. doi: 10.1136/jcp.32.7.675.

A series of 12 patients with a rare malignant lymphoma containing numerous epithelioid histiocytes (MLEH), originally believed to be an atypical variant of Hodgkin's disease, is described. Clinicopathological studies suggest MLEH is a distinct entity among the non-Hodgkin's lymphomas which is generally resistant to therapy and has an unfavourable prognosis. Differentiation of the disease from angioimmunoblastic lymphadenopathy and Hodgkin's disease is discussed. In the necropsy case MLEH had transformed into a malignant lymphoma of histiocytic type.

本文描述了一系列12例患有罕见恶性淋巴瘤的患者，该淋巴瘤含有大量上皮样组织细胞（MLEH），最初被认为是霍奇金病的一种非典型变体。临床病理研究表明，MLEH是一种独特的非霍奇金淋巴瘤，通常对治疗耐药且预后不良。文中讨论了该疾病与血管免疫母细胞性淋巴结病和霍奇金病的鉴别诊断。在尸检病例中，MLEH已转变为组织细胞型恶性淋巴瘤。