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Triton-induced hyperlipidemia in rats as an animal model for screening hypolipidemic drugs.

作者信息

Schurr P E, Schultz J R, Parkinson T M

出版信息

Lipids. 1972 Jan;7(1):68-74. doi: 10.1007/BF02531272.

DOI:10.1007/BF02531272
PMID:5013174
Abstract
摘要

相似文献

1
Triton-induced hyperlipidemia in rats as an animal model for screening hypolipidemic drugs.以 Triton 诱导的大鼠高脂血症作为筛选降血脂药物的动物模型。
Lipids. 1972 Jan;7(1):68-74. doi: 10.1007/BF02531272.
2
Differential effects of benzodioxane, chroman and dihydrobenzofuran analogs of clofibrate in a Triton hyperlipemic rat model.
Lipids. 1973 Jul;8(7):378-84. doi: 10.1007/BF02531712.
3
Pharmacokinetics and hypolipidemic activity of clofibrate-nicotinic acid combinations in rats.氯贝丁酯-烟酸组合在大鼠体内的药代动力学及降血脂活性
Biochem Pharmacol. 1979 Apr 1;28(7):1163-7. doi: 10.1016/0006-2952(79)90323-x.
4
A comparison of hypolipidemic drugs in the prevention of an orotic acid fatty liver.降血脂药物预防乳清酸脂肪肝的比较。
Biochem Pharmacol. 1972 Apr 15;21(8):1127-34. doi: 10.1016/0006-2952(72)90106-2.
5
Effects of various hypolipidemic drugs on fatty acid composition of liver and serum lipids.
Adv Exp Med Biol. 1975;63:349-57. doi: 10.1007/978-1-4684-3258-9_25.
6
3-Hydroxy-3-methylglutaric acid and triton-induced hyperlipidemia in rats.3-羟基-3-甲基戊二酸与 Triton 诱导的大鼠高脂血症
Experientia. 1976 Sep 15;32(9):1178-9. doi: 10.1007/BF01927612.
7
Preliminary evaluation of the hypolipidemic effects in man of a new phenolic ether (Su-13437, CIBA).
J Atheroscler Res. 1969 Jul-Aug;10(1):103-6. doi: 10.1016/s0368-1319(69)80088-8.
8
Hypolipidemic effect of a new aryloxy compound, S-8527, in experimental animals.新型芳氧基化合物S-8527对实验动物的降血脂作用。
Jpn J Pharmacol. 1974 Jun;24(3):407-14. doi: 10.1254/jjp.24.407.
9
The effect of niceritrol (pentaerythritoltetranicotinate) and clofibrate upon hyperlipemia and atherosclerosis induced in rabbits by cholesterol-free semisynthetic diets.
Atherosclerosis. 1974 Nov-Dec;20(3):453-67. doi: 10.1016/0021-9150(74)90027-6.
10
The effect of hypolipidemic drugs on plasma lipoproteins.
Annu Rev Pharmacol Toxicol. 1977;17:499-510. doi: 10.1146/annurev.pa.17.040177.002435.

引用本文的文献

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Combinatorial effects of Zingiber officinale and Citrus limon juices: Hypolipidemic and antioxidant insights from in vivo, in vitro, and in silico investigations.生姜和柠檬果汁的联合作用：体内、体外和计算机模拟研究的降血脂及抗氧化见解
PLoS One. 2025 Sep 12;20(9):e0319721. doi: 10.1371/journal.pone.0319721. eCollection 2025.
2
Novel carboxamide derivatives increase lipoprotein lipase gene expression in endothelial and adipose tissues of triton WR- 1339 induced hyperlipidemic rats.新型羧酰胺衍生物可增加 Triton WR - 1339 诱导的高脂血症大鼠内皮组织和脂肪组织中脂蛋白脂肪酶基因的表达。
Naunyn Schmiedebergs Arch Pharmacol. 2025 Apr 26. doi: 10.1007/s00210-025-04174-z.
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1
Antituberculous effect of certain surface-active polyoxyethylene ethers in mice.某些表面活性聚氧乙烯醚对小鼠的抗结核作用。
Nature. 1951 Jul 28;168(4265):150-3. doi: 10.1038/168150a0.
2
Charts of the power function for analysis of variance tests, derived from the non-central F-distribution.源自非中心F分布的用于方差分析检验的幂函数图表。
Biometrika. 1951 Jun;38(1-2):112-30.
3
EFFECTS OF ALPHA-P-CHLOROPHENOXYISOBUTYRYL ETHYL ESTER (CPIB) WITH AND WITHOUT ANDROSTERONE ON CHOLESTEROL BIOSYNTHESIS IN RAT LIVER.α-对氯苯氧基异丁酰乙酯（CPIB）单独及与雄甾酮合用对大鼠肝脏胆固醇生物合成的影响
Assessing lipid-lowering and plasma cholesteryl ester transfer protein activity of and β-Sitosterol following administration to triton WR1339- treated rats.
评估给予经Triton WR1339处理的大鼠后，α-和β-谷甾醇的降脂作用及血浆胆固醇酯转移蛋白活性。
Food Sci Nutr. 2024 Oct 24;12(11):9788-9798. doi: 10.1002/fsn3.4471. eCollection 2024 Nov.
4
Optimization of the proportions of advantageous components in the hypolipidemic "bioequivalent substance system" of Jiang-Zhi-Ning and its mechanism of action.降脂“生物等效物质体系”中降脂优势成分比例优化及其作用机制的研究。
Pharm Biol. 2023 Dec;61(1):1374-1386. doi: 10.1080/13880209.2023.2243999.
5
Bioenhancing effects of naringin on atorvastatin.柚皮苷对阿托伐他汀的生物增强作用。
ADMET DMPK. 2019 Jun 6;7(3):174-182. doi: 10.5599/admet.647. eCollection 2019.
6
Effect of Aqueous Extract and Polyphenol Fraction Derived from Leaves on Acute Hyperlipidemia in the Syrian Golden Hamsters.叶水提取物和多酚组分对叙利亚金仓鼠急性高脂血症的影响
Evid Based Complement Alternat Med. 2020 Mar 28;2020:3282596. doi: 10.1155/2020/3282596. eCollection 2020.
7
Antihyperlipidemic Effect, Identification and Isolation of the Lipophilic Components from Artemisia integrifolia.黄花蒿的降脂作用及其脂溶性成分的鉴定与分离。
Molecules. 2019 Feb 17;24(4):725. doi: 10.3390/molecules24040725.
8
Atorvastatin calcium inclusion complexation with polysaccharide arabinogalactan and saponin disodium glycyrrhizate for increasing of solubility and bioavailability.阿伐他汀钙与多糖阿拉伯半乳聚糖和甘草酸二钠形成包合物以提高溶解度和生物利用度。
Drug Deliv Transl Res. 2018 Oct;8(5):1200-1213. doi: 10.1007/s13346-018-0565-x.
9
Pharmacological Screening of for Antihyperlipidemic Activity in Triton X-100 Induced Hyperlipidemia Rat Model.在 Triton X - 100 诱导的高脂血症大鼠模型中对[具体药物名称未给出]进行抗高脂血症活性的药理筛选。
Pharmacognosy Res. 2017 Dec;9(Suppl 1):S34-S40. doi: 10.4103/pr.pr_37_17.
10
Hypolipidemic Activity of Cassia tora Seeds in Hyperlipidemic Rats.决明子种子对高脂血症大鼠的降血脂活性
Indian J Clin Biochem. 2015 Jan;30(1):78-83. doi: 10.1007/s12291-013-0412-2. Epub 2014 Jan 24.
J Lipid Res. 1965 Jul;6:369-76.
4
PERSISTENCE OF THE INHIBITORY EFFECT OF NICOTINIC ACID ON CATECHOLAMINE-STIMULATED LIPID MOBILIZATION DURING PROLONGED TREATMENT WITH NICOTINIC ACID.烟酸长期治疗期间，烟酸对儿茶酚胺刺激的脂质动员的抑制作用的持续性。
J Atheroscler Res. 1965 Jul-Aug;5(4):436-9. doi: 10.1016/s0368-1319(65)80080-1.
5
THE EFFECT OF METHYL CELLULOSE ON THE RETICULOENDOTHELIAL SYSTEM.甲基纤维素对网状内皮系统的作用
J Reticuloendothel Soc. 1964 Jan;1:68-76.
6
Comparative studies on hypocholesteremic agents.降胆固醇药物的比较研究。
Am J Clin Nutr. 1962 Apr;10:277-84. doi: 10.1093/ajcn/10.4.277.
7
Triton hypercholesteremia: cause or consequence of augmented cholesterol synthesis.海卫一高胆固醇血症：胆固醇合成增加的原因还是结果。
Am J Physiol. 1963 Jun;204:1100-2. doi: 10.1152/ajplegacy.1963.204.6.1100.
8
Influence of thyroid hormones and related compounds on cholesterol biosynthesis and degradation: a review.甲状腺激素及相关化合物对胆固醇生物合成与降解的影响：综述
Metabolism. 1960 Nov;9:984-94.
9
Triton hyperlipemia in dogs. II. Atheroscieross, diffuse lipidosis, and deletion of fat stores produced by prolonged administration of the non-tonic surface-active agent.犬类的 Triton 高脂血症。II. 长期给予非滋补性表面活性剂所产生的动脉粥样硬化、弥漫性脂质沉积和脂肪储备缺失。
J Exp Med. 1961 Sep 1;114(3):279-94. doi: 10.1084/jem.114.3.279.
10
Mechanism underlying hypercholesteremia induced by triton WR-1339.曲拉通WR - 1339诱导高胆固醇血症的潜在机制。
Am J Physiol. 1957 Sep;190(3):439-45. doi: 10.1152/ajplegacy.1957.190.3.439.