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猫颈上神经节电刺激后突触的形态学改变

Morphologic alterations of synapses in electrically stimulated superior cervical ganglia of the cat.

作者信息

Pysh J J, Wiley R G

出版信息

Science. 1972 Apr 14;176(4031):191-3. doi: 10.1126/science.176.4031.191.

DOI:10.1126/science.176.4031.191
PMID:5014443
Abstract

Prolonged preganglionic stimulation produces marked ultrastructural changes in presynaptic endings, which develop larger zones of contact with post-synaptic dendrites. Profiles of such endings, compared to controls, have fewer synaptic vesicles, similar areas, and greater circumferences. These results are compatible with the hypothesis that synaptic vesicles become incorporated into the plasma membrane during stimulation.

摘要

长时间的节前刺激会使突触前末梢产生明显的超微结构变化,这些末梢与突触后树突形成更大的接触区域。与对照组相比,此类末梢的形态显示突触小泡数量减少、面积相似但周长更大。这些结果与以下假设相符:在刺激过程中,突触小泡会融入质膜。

相似文献

1
Morphologic alterations of synapses in electrically stimulated superior cervical ganglia of the cat.猫颈上神经节电刺激后突触的形态学改变
Science. 1972 Apr 14;176(4031):191-3. doi: 10.1126/science.176.4031.191.
2
Effects of stimulation and hemicholinium (HC-3) on the fine structure of nerve endings in the superior cervical ganglion of the cat.刺激和半胆碱(HC - 3)对猫颈上神经节神经末梢精细结构的影响。
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Fine structural alterations of presynaptic endings in the superior cervical ganglion of the cat after exhausting preganglionic stimulation.猫颈上神经节在节前刺激耗竭后突触前终末的超微结构改变。
Experientia. 1970 Jun 15;26(6):629-30. doi: 10.1007/BF01898728.
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Synaptic vesicle depletion and recovery in cat sympathetic ganglia electrically stimulated in vivo. Evidence for transmitter secretion by exocytosis.猫交感神经节在体内电刺激时突触小泡的耗竭与恢复。关于通过胞吐作用分泌递质的证据。
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Time course and frequency dependence of synaptic vesicle depletion and recovery in electrically stimulated sympathetic ganglia.电刺激交感神经节中突触小泡耗竭与恢复的时间进程及频率依赖性
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Detachment of structurally intact nerve endings from chromatolytic neurones of rat superior cervical ganglion during the depression of synaptic transmission induced by post-ganglionic axotomy.在节后轴突切断诱导的突触传递抑制过程中,大鼠颈上神经节的色解体神经元的结构完整神经末梢的脱离。
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The effects of nerve stimulation and hemicholinium on synaptic vesicles at the mammalian euromuscular junction.神经刺激和半胆碱对哺乳动物神经肌肉接头处突触小泡的影响。
J Physiol. 1970 Mar;207(1):31-50. doi: 10.1113/jphysiol.1970.sp009046.

引用本文的文献

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2
Morphological changes in presynaptic terminals of the chick ciliary ganglion after stimulation in vivo. A stereological study showing a net loss of total membrane.体内刺激后鸡睫状神经节突触前终末的形态学变化。一项体视学研究显示总膜的净损失。
Exp Brain Res. 1981;43(3-4):439-46. doi: 10.1007/BF00238388.
3
Synaptic vesicle depletion and recovery in cat sympathetic ganglia electrically stimulated in vivo. Evidence for transmitter secretion by exocytosis.
猫交感神经节在体内电刺激时突触小泡的耗竭与恢复。关于通过胞吐作用分泌递质的证据。
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Ultrastructure of muscle in stiff-man syndrome.僵人综合征患者肌肉的超微结构
Virchows Arch A Pathol Anat Histol. 1974;362(3):207-21. doi: 10.1007/BF00432195.
5
Some effects of preganglionic nerve stimulation on synaptic vesicle populations in the rat superior cervical ganglion.节前神经刺激对大鼠颈上神经节中突触小泡群体的一些影响。
J Physiol. 1973 Dec;235(2):317-31. doi: 10.1113/jphysiol.1973.sp010389.
6
Turnover of transmitter and synaptic vesicles at the frog neuromuscular junction.青蛙神经肌肉接头处递质和突触小泡的周转
J Cell Biol. 1973 May;57(2):499-524. doi: 10.1083/jcb.57.2.499.
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Evidence for recycling of synaptic vesicle membrane during transmitter release at the frog neuromuscular junction.关于青蛙神经肌肉接头处递质释放过程中突触小泡膜循环利用的证据。
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Formation of synaptic vesicles in the superior cervical ganglion of cat: choline dependency.
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The effects of prolonged repetitive stimulation in hemicholinium on the frog neuromuscular junction.毒扁豆碱中长时间重复刺激对青蛙神经肌肉接头的影响。
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Visualization of stimulated nerve endings by preferential calcium accumulation of mitochondria.通过线粒体的优先钙积累来可视化受刺激的神经末梢。
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