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对女性进行常规风疹抗体检测的必要性。

The need for routine rubella antibody testing of women.

作者信息

Chin J, Magoffin R L, Lennette E H

出版信息

Calif Med. 1972 Mar;116(3):9-13.

Abstract

Results of rubella antibody tests performed by the California State Viral and Rickettsial Disease Laboratory on blood specimens collected in 1968 and 1969 from school children and women of childbearing age showed a slightly lower prevalence of rubella antibody in California than reported from most other areas of the United States. Among women of childbearing age, rubella hemagglutination-inhibition (hi) antibody was found in 72 percent of those tested in California compared with 80 percent to 90 percent in other areas of the country. Rubella antibody testing services offered by the State Virus Laboratory included situations in which a pregnant woman was exposed to a suspected case of rubella. It was shown that very few of these exposures constitute a significant risk to the fetus as most of the women already possessed antibody to rubella from past infection and in many instances the exposures were not to actual cases of rubella. The results of this study emphasized the urgency of obtaining blood specimens from pregnant women as soon as possible after exposure to rubella or development of symptoms of rubella. The urgency and anxiety attending these situations can largely be obviated if routine rubella antibody testing of women is carried out prior to pregnancy or at the first prenatal visit.

摘要

加利福尼亚州病毒及立克次体病实验室对1968年和1969年采集的学龄儿童及育龄妇女血液样本进行的风疹抗体检测结果显示,加利福尼亚州风疹抗体的流行率略低于美国其他大多数地区所报告的水平。在育龄妇女中,加利福尼亚州72%接受检测的人发现有风疹血凝抑制(HI)抗体,而美国其他地区这一比例为80%至90%。州病毒实验室提供的风疹抗体检测服务包括孕妇接触疑似风疹病例的情况。结果表明,这些接触中很少会对胎儿构成重大风险,因为大多数妇女过去感染风疹后已拥有抗体,而且在许多情况下,接触的并非实际风疹病例。这项研究的结果强调了在孕妇接触风疹或出现风疹症状后尽快采集血液样本的紧迫性。如果在怀孕前或首次产前检查时对妇女进行常规风疹抗体检测,这些情况下的紧迫性和焦虑在很大程度上可以消除。

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