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耶路撒冷地区先天性风疹监测及风疹免疫状况

Surveillance of congenital rubella and the immunity status to rubella in the Jerusalem area.

作者信息

Isacsohn M, Rudensky B, Eidelman A I, Paz E, Weintraub G, Nubani N, Swartz T A

出版信息

Isr J Med Sci. 1983 Oct;19(10):929-33.

PMID:6363348
Abstract

A retrospective study on the incidence of congenital rubella (CR) in the past 10 years in the Jerusalem area was conducted. After the 1972 epidemic, which resulted in 48 cases of congenital rubella, few sporadic cases of CR appeared each year, and in the 1978-79 period the number of CR cases was relatively small. Immunity to rubella in different categories of population (children 3 months to 18 years, college students, nurses in pediatric, newborn and intensive care units, student nurses, and women of childbearing age) was determined by hemolysis in gel (HIG) and hemagglutination inhibition (HI) methods. Susceptibility was defined as an absence of antibody at a dilution of 1:16 in HI, and hemolysis of less than 7 mm in the HIG test. Compared with previous studies on the incidence of antibodies to rubella in women of childbearing age, a mild decrease in the percentage of sero-negative women was found.

摘要

对耶路撒冷地区过去10年先天性风疹(CR)的发病率进行了一项回顾性研究。1972年疫情导致48例先天性风疹病例后,每年出现少数散发性CR病例,在1978 - 1979年期间,CR病例数量相对较少。通过凝胶溶血(HIG)和血凝抑制(HI)方法测定了不同人群(3个月至18岁儿童、大学生、儿科、新生儿和重症监护病房护士、实习护士以及育龄妇女)对风疹的免疫力。易感性定义为HI试验中稀释度为1:16时无抗体,且HIG试验中溶血小于7毫米。与之前关于育龄妇女风疹抗体发病率的研究相比,发现血清阴性妇女的百分比略有下降。

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