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含有互补多核苷酸链的两种腺相关病毒颗粒的分离。

Separation of two types of adeno-associated virus particles containing complementary polynucleotide chains.

作者信息

Berns K I, Adler S

出版信息

J Virol. 1972 Feb;9(2):394-6. doi: 10.1128/JVI.9.2.394-396.1972.

DOI:10.1128/JVI.9.2.394-396.1972
PMID:5014934
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC356306/
Abstract

An adeno-associated virus containing bromodeoxyuridine-substituted deoxyribonucleic acid has been fractionated by equilibrium centrifugation in CsCl into two classes of virions which contain complementary polynucleotide chains.

摘要

一种含有溴脱氧尿苷取代的脱氧核糖核酸的腺相关病毒已通过在氯化铯中进行平衡离心分离成两类含有互补多核苷酸链的病毒粒子。

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本文引用的文献

1
Amino acid metabolism in mammalian cell cultures.哺乳动物细胞培养中的氨基酸代谢
Science. 1959 Aug 21;130(3373):432-7. doi: 10.1126/science.130.3373.432.
2
Evidence for a single-stranded adenovirus-associated virus genome: isolation and separation of complementary single strands.单链腺病毒相关病毒基因组的证据：互补单链的分离与纯化
J Virol. 1970 Jun;5(6):693-9. doi: 10.1128/JVI.5.6.693-699.1970.
3
Plus and minus single-stranded DNA separately encapsidated in adeno-associated satellite virions.分别包裹在腺相关卫星病毒粒子中的正链和负链单链DNA。
Science. 1969 Dec 5;166(3910):1280-2. doi: 10.1126/science.166.3910.1280.
4
Evidence for a single-stranded adenovirus-associated virus genome: formation of a DNA density hybrid on release of viral DNA.单链腺病毒相关病毒基因组的证据：病毒DNA释放时形成DNA密度杂种。
Proc Natl Acad Sci U S A. 1969 Nov;64(3):863-9. doi: 10.1073/pnas.64.3.863.
5
Nucleic acid from an adeno-associated virus: chemical and physical studies.来自腺相关病毒的核酸：化学和物理研究。
Proc Natl Acad Sci U S A. 1966 Jul;56(1):86-92. doi: 10.1073/pnas.56.1.86.
6
Physicochemical characterization of adeno-associated satellite virus type 4 and its nucleic acid.4型腺相关卫星病毒及其核酸的物理化学特性
J Virol. 1967 Oct;1(5):980-7. doi: 10.1128/JVI.1.5.980-987.1967.
7
The DNA of a minute virus of mice.小鼠微小病毒的DNA
J Gen Virol. 1969 Jan;4(1):37-46. doi: 10.1099/0022-1317-4-1-37.