Drouhault R, Bethous C, Blanquet P
C R Acad Hebd Seances Acad Sci D. 1975 May 12;280(18):2141-3.
The intravenous injection that was given to rabbits which consisted of 0,5 mg of a common heptapeptide to ACTH4-10, BETA MSH11-17 hormones, and to beta lipotropic47-53 hormone (beta LPH47-53) was followed at the end of an hour by an augmentation of 70% of total lipids, and at the end of two hours by a lowering of calcemia (around 27%) and of phosphoremia (20%). The injection of a tetrapeptide corresponding to only ACTH7-10 bound to a nitrobenzylhydralamin and in presence of a Freund adjuvants has provoked the formation of corresponding antibodies.
给兔子静脉注射由0.5毫克常见的七肽组成的物质,该七肽包含促肾上腺皮质激素4 - 10、β-促黑素11 - 17激素以及β-促脂素47 - 53激素(β-LPH47 - 53)。一小时后,总脂质增加了70%,两小时后,血钙降低(约27%),血磷降低(20%)。注射仅对应促肾上腺皮质激素7 - 10且与硝基苄基肼结合并存在弗氏佐剂的四肽,引发了相应抗体的形成。