Richter W O, Schwandt P
Life Sci. 1983;33 Suppl 1:747-50. doi: 10.1016/0024-3205(83)90610-0.
Since there is accumulating evidence for metabolic functions of proopiocortin peptides, we investigated 42 partial sequences for their lipolytic activity in isolated rabbit fat cells. 4 lipolytic active centers can be suggested: in the N-terminal part of proopiocortin (not gamma- and delta-MSH), in the N-terminal region of ACTH (ACTH 4-1o), in the beta-MSH sequence of beta-lipotropin and in the C-terminal region of beta-endorphin.
由于有越来越多的证据表明促阿片皮质素肽具有代谢功能，我们研究了42个部分序列在分离的兔脂肪细胞中的脂解活性。可以推测出4个脂解活性中心：位于促阿片皮质素的N端部分（非γ-和δ-促黑素细胞激素）、促肾上腺皮质激素的N端区域（促肾上腺皮质激素4-10）、β-促脂素的β-促黑素细胞激素序列以及β-内啡肽的C端区域。
