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[Antigenic determinants of beta-LPH, beta-MSH, alpha-endorphin, ACTH and alpha-MSH revealed by anti-beta-endorphin in neurons of the human infundibular nucleus].

作者信息

Bloch B, Bugnon C, Fellmann D, Lenys D

出版信息

C R Acad Hebd Seances Acad Sci D. 1978 Oct 30;287(11):1019-22.

PMID:84718
Abstract

Comparison of adjacent serial sections of the tubero-infundibular region of Human adult hypothalamus demonstrates that the same perikarya, axons and terminals are stained both with anti-beta-endorphin and anti 17-39 ACTH antisera. The most immunoreactive of these neurons are also revealed with anti alpha-endorphin, anti alpha and beta-MSH, anti-1-24 ACTH and anti beta-LPH. These results suggest that neurons of the infundibular nucleus can store and probably secrete peptide similar to propiocortin or fragment(s) of this molecule.

摘要

相似文献

1
[Antigenic determinants of beta-LPH, beta-MSH, alpha-endorphin, ACTH and alpha-MSH revealed by anti-beta-endorphin in neurons of the human infundibular nucleus].
C R Acad Hebd Seances Acad Sci D. 1978 Oct 30;287(11):1019-22.
2
Infundibular neurons of the human hypothalamus simultaneously reactive with antisera against endorphins, ACTH, MSH and beta-LPH.人类下丘脑的漏斗神经元可同时与抗内啡肽、促肾上腺皮质激素、促黑素细胞激素及β-促脂解素的抗血清发生反应。
Cell Tissue Res. 1979 Jun 27;199(2):177-96. doi: 10.1007/BF00236130.
3
Neurons of the rat hypothalamus reactive with antisera against endorphins, ACTH, MSH and beta-LPH.大鼠下丘脑神经元与抗内啡肽、促肾上腺皮质激素、促黑素细胞激素和β-促脂解素的抗血清发生反应。
Cell Tissue Res. 1979;204(1):1-15. doi: 10.1007/BF00235160.
4
[Immunocytologic analysis, in rat hypothalamus, of neurons producing peptides related to endorphin, ACTH, MSH and beta-LPH. Comparison with other peptidergic and monoaminergic neurons].[大鼠下丘脑内产生与内啡肽、促肾上腺皮质激素、促黑素细胞激素和β-促脂解素相关肽的神经元的免疫细胞分析。与其他肽能和单胺能神经元的比较]
C R Seances Soc Biol Fil. 1979;173(4):719-24.
5
Characterization of pro-ACTH/endorphin-derived peptides in rat hypothalamus.大鼠下丘脑促肾上腺皮质激素原/内啡肽衍生肽的特性分析。
J Neurosci. 1986 Mar;6(3):837-49. doi: 10.1523/JNEUROSCI.06-03-00837.1986.
6
Immunocytochemical localization of pro gamma MSH, gamma MSH, ACTH and beta endorphin/beta lipotrophin in the fetal sheep pituitary: an ontogenetic study.胎儿绵羊垂体中前γ-促黑素、γ-促黑素、促肾上腺皮质激素及β-内啡肽/β-促脂解素的免疫细胞化学定位：一项个体发生学研究
J Dev Physiol. 1986 Oct;8(5):355-68.
7
[Cyto-immunological study in the human fetuses and adults of hypothalamic neurons able to synthesize different peptides related to endorphins, ACTH, LPH and MSH from a common precursor molecule (author's transl)].[关于人类胎儿和成人下丘脑神经元的细胞免疫学研究，这些神经元能够从一个共同的前体分子合成与内啡肽、促肾上腺皮质激素、促脂解素和促黑素相关的不同肽类（作者译）]
J Physiol (Paris). 1979 May;75(1):67-87.
8
Immunocytochemical evidence that the same neurons in the human infundibular nucleus are stained with anti-endorphins and antisera of other related peptides.免疫细胞化学证据表明，人类漏斗核中的相同神经元被抗内啡肽和其他相关肽的抗血清染色。
Neurosci Lett. 1978 Nov;10(1-2):147-52. doi: 10.1016/0304-3940(78)90026-5.
9
Immunological characterization of endorphins, adrenocorticotropin, and melanotropins in frog hypothalamus.蛙下丘脑内啡肽、促肾上腺皮质激素和促黑素细胞激素的免疫学特性
Gen Comp Endocrinol. 1983 Aug;51(2):246-54. doi: 10.1016/0016-6480(83)90078-3.
10
Evidence for a common precursor for alpha MSH and beta-endorphin in the intermediate lobe of the pituitary of the reptile Anolis carolinensis.关于卡罗来纳安乐蜥垂体中间叶中α-促黑素细胞激素（α-MSH）和β-内啡肽存在共同前体的证据。
Peptides. 1982 Nov-Dec;3(6):925-35. doi: 10.1016/0196-9781(82)90061-4.

引用本文的文献

1
Identification and immunocytochemical localization of a human adult brain-specific antigen (HABSA).一种人类成脑特异性抗原（HABSA）的鉴定及免疫细胞化学定位
Histochemistry. 1983;79(1):117-30. doi: 10.1007/BF00494349.
2
Immunohistochemical localisation of substances reactive to antisera against alpha- and beta-endorphin and met-enkephalin in the brain of Rana temporaria L.对林蛙大脑中与抗α-内啡肽、β-内啡肽和甲硫氨酸脑啡肽抗血清发生反应的物质进行免疫组织化学定位
Cell Tissue Res. 1981;217(1):79-92. doi: 10.1007/BF00233828.
3
Neurons of the rat hypothalamus reactive with antisera against endorphins, ACTH, MSH and beta-LPH.
大鼠下丘脑神经元与抗内啡肽、促肾上腺皮质激素、促黑素细胞激素和β-促脂解素的抗血清发生反应。
Cell Tissue Res. 1979;204(1):1-15. doi: 10.1007/BF00235160.
4
Immunoreactivity for beta-endorphin in LH-RH neurons of the fetal human hypothalamus.人胎儿下丘脑促性腺激素释放激素（LH-RH）神经元中β-内啡肽的免疫反应性
Cell Tissue Res. 1979;203(2):201-7. doi: 10.1007/BF00237234.
5
Infundibular neurons of the human hypothalamus simultaneously reactive with antisera against endorphins, ACTH, MSH and beta-LPH.人类下丘脑的漏斗神经元可同时与抗内啡肽、促肾上腺皮质激素、促黑素细胞激素及β-促脂解素的抗血清发生反应。
Cell Tissue Res. 1979 Jun 27;199(2):177-96. doi: 10.1007/BF00236130.