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对澳大利亚献血者进行(与肝炎相关的)抗原及其抗体的全面筛查。

Total screening of blood donations for Australia (hepatitis associated) antigen and its antibody.

作者信息

Wallace J, Milne G R, Barr A

出版信息

Br Med J. 1972 Mar 11;1(5801):663-4. doi: 10.1136/bmj.1.5801.663.

Abstract

During a period of one year all of 105,724 blood donations were tested for Australia (Au) antigen and its antibody by rapid immunoelectro-osmophoresis-86 (1 in 1,229) were positive for antigen and 67 (1 in 1,578) positive for antibody. Second donations by previously negative donors reduce the overall incidence of positives. Men prisoners have a significantly higher incidence of Au antigen (1 in 153) than non-institutionalized men (1 in 803). The latter have a significantly higher incidence of antigen than women (1 in 2,019). Only one antigen-positive donor was incubating acute viral hepatitis. Failure to detect one strong and one weak antigen was responsible for two cases of posttransfusion Au-antigen-positive hepatitis.

摘要

在一年时间里,对澳大利亚(Au)抗原及其抗体进行了检测的105,724份献血样本中,有86份(每1229份中有1份)抗原呈阳性,67份(每1578份中有1份)抗体呈阳性。先前检测为阴性的献血者再次献血后,阳性的总体发生率有所降低。男性囚犯中Au抗原的发生率(每153人中有1人)显著高于非在押男性(每803人中有1人)。后者的抗原发生率显著高于女性(每2019人中有1人)。只有一名抗原呈阳性的献血者正处于急性病毒性肝炎潜伏期。未能检测出一种强抗原和一种弱抗原导致了两例输血后Au抗原阳性肝炎病例。

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