大鼠支气管上皮免受烟草烟雾的侵害。
Protection of rat bronchial epithelium against tobacco smoke.
作者信息
Jones R, Bolduc P, Reid L
出版信息
Br Med J. 1972 Apr 15;2(5806):142-4. doi: 10.1136/bmj.2.5806.142.
Abstract
Addition to tobacco of phenylmethyloxadiazole (PMO) protects rats against some of the adverse effects of exposure to cigarette smoke. Two groups of 15 rats were exposed to 25 cigarettes a day for 24 days; the group whose cigarette included PMO showed less immediate distress after exposure, a smaller tracheal goblet cell count, less thickening of the tracheal epithelium, and less cells in mitosis than those exposed to ordinary tobacco.
摘要
在烟草中添加苯甲基恶二唑（PMO）可保护大鼠免受接触香烟烟雾的一些不利影响。两组各15只大鼠每天暴露于25支香烟中，持续24天；香烟中含有PMO的组在暴露后表现出的即时痛苦较轻，气管杯状细胞计数较少，气管上皮增厚较少，处于有丝分裂的细胞也比暴露于普通烟草的组少。
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