Mishima K, Ohta T, Kitagawa N, Harada H
Jpn J Antibiot. 1979 Sep;32(9):960-5.
Clinical studies on apalcillin (APPC), a new broad spectrum semisynthetic penicillin developed in Japan, were carried out, and the following results were obtained. APPC was administered to three patients with serious biliary tract infections by intramuscular or intravenous injection at daily dosage of 2. Therapeutic responses were excellent in all cases, and no side effects and abnormalities of laboratory findings were observed. APPC was considered to be an excellent drug for the treatment of biliary tract infections.
对在日本研发的新型广谱半合成青霉素阿帕西林（APPC）进行了临床研究，获得了以下结果。以每日2的剂量通过肌肉注射或静脉注射给3例严重胆道感染患者使用阿帕西林。所有病例的治疗反应均极佳，未观察到副作用及实验室检查结果异常。阿帕西林被认为是治疗胆道感染的一种优良药物。
