Minamitani M, Hachimori K
Jpn J Antibiot. 1978 Jul;31(7):383-8.
Clinical study of PC-904 was performed in 8 children with infectious diseases and the following results were obtained. 1) The patients treated with PC-904 were each one case of acute pharyngitis, lacunar tonsillitis, scarlet fever, phlegmone, acute bronchitis and lung abscess, and 2 cases of bronchopneumonia. 2) The administration methods were drip infusion, one-shot intravenous injection and the combined use of these administrations. The daily dosage varied from 30 to 49 mg/kg in 3 cases and from 50 to 70 mg/kg in 3 cases, and was 227 mg/kg in 1 case. 3) Clinical evaluation was examined in 7 cases and 57.1% of effectiveness was obtained. Out of 2 cases of pneumonia, one case with the causative organism of My. pneumoniae was excluded from the clinical evaluation. 4) No side effects were observed in all 8 cases treated with PC-904.
对8名患有传染病的儿童进行了PC - 904的临床研究，获得了以下结果。1）接受PC - 904治疗的患者分别为急性咽炎、陷窝性扁桃体炎、猩红热、蜂窝织炎、急性支气管炎和肺脓肿各1例，支气管肺炎2例。2）给药方法为静脉滴注、单次静脉注射以及这些给药方式的联合使用。3例患者的日剂量为30至49毫克/千克，3例为50至70毫克/千克，1例为227毫克/千克。3）对7例患者进行了临床评估，有效率为57.1%。在2例肺炎患者中，1例肺炎支原体致病的患者被排除在临床评估之外。4）接受PC - 904治疗的所有8例患者均未观察到副作用。
