Aoyama R, Nagata K, Izumi Y, Kudo M, Sato S
Jpn J Antibiot. 1978 Jul;31(7):363-5.
A clinical study of PC-904 was performed and the following results were obtained. 1) PC-904 was intravenously administered at the daily dosage of 20 approximately 120 mg/kg to 13 children; urinary tract infection (10 cases), acute pneumonia (1 case), sepsis (1 case) and purulent meningitis (1 case). The overall efficacy rate was 46.2%. 2) As to adverse reaction, eosinophilia was noted only in 2 patients. One neonate was treated with this drug, but no side effects were observed. 3) It was considered that PC-904 was a useful antibiotic drug for the second choice rather than the first.
对PC - 904进行了一项临床研究，并获得了以下结果。1）以每日约20至120mg/kg的剂量对13名儿童静脉注射PC - 904；这些儿童患有尿路感染（10例）、急性肺炎（1例）、败血症（1例）和化脓性脑膜炎（1例）。总有效率为46.2%。2）关于不良反应，仅2例患者出现嗜酸性粒细胞增多。一名新生儿接受了该药物治疗，但未观察到副作用。3）认为PC - 904是一种有用的二线抗生素药物，而非一线药物。
