Church M W
Electroencephalogr Clin Neurophysiol. 1975 Jul;39(1):1-7. doi: 10.1016/0013-4694(75)90121-2.
Modified period analysis was applied to all-night sleep recordings from 14 young adult males. The modifications involved addition of measures of integrated amplitude and of time in frequency band to the zero crossings and zero counts of the first derivative. The analysis was directed toward changes in the characteristics of delta activity (0--3 c/sec) across the night. Delta shifted toward lower frequencies and decreased in amplitude as sleep progressed. These trends were apparent in mean values for successive periods of slow-wave sleep (SSWPs). For epochs of record classified as stage 4 EEG, these trends were seen both within and across SSWPs. The physiological significance of these changes is unknown. We suggest that they may reflect the kinetics of the metabolic processes underlying sleep. Whatever their theoretical significance, the present results provide new, normative features of the sleep EEG which are not evident in sleep stage classification. The trends we observed appear sufficiently reliable to merit empirical investigation as a function of age, clinical state, or the administration of drugs in addition to further studies aimed at determining their biological significance.
改良周期分析法应用于14名年轻成年男性的整夜睡眠记录。改良内容包括在一阶导数的过零次数和零计数基础上，增加积分振幅和频段时间的测量。该分析旨在研究夜间δ波活动（0 - 3赫兹）特征的变化。随着睡眠进程，δ波向低频移动且振幅减小。这些趋势在连续慢波睡眠期（SSWPs）的平均值中很明显。对于分类为脑电图第4阶段的记录片段，这些趋势在SSWPs内和跨SSWPs时均可见。这些变化的生理意义尚不清楚。我们认为它们可能反映了睡眠潜在代谢过程的动力学。无论其理论意义如何，目前的结果提供了睡眠脑电图新的规范特征，这些特征在睡眠阶段分类中并不明显。我们观察到的趋势似乎足够可靠，除了旨在确定其生物学意义的进一步研究外，还值得作为年龄、临床状态或药物给药的函数进行实证研究。
