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[咪康唑在念珠菌病预防和治疗中的经验]

[Experiences with miconazole in the prevention and therapy of candidiasis].

作者信息

Grulich M, Dörffel W, Reuter G, Gemeinhardt H

出版信息

Padiatr Grenzgeb. 1979;18(3):165-75.

PMID:503539
Abstract
  1. The treatment of 26 children suffering from haemoblastoses and tumors by the antimycotic Miconazol is reported on. 2. The application took place prophylactically as well as therapeutically by an oral or intravenous administration. Mycological examinations (stools, urine, throat swab, blood) have been carried through before, during and after the treatment in weekly intervals. 3. The result of treatment is altogether to be called good, invasive mycoses have been prevented and proved Blastomyces infections successfully treated. 4. Side effects like nausea and vomiting were observed only in one case, damages of the haematopoietic system, the liver and kidneys could not have been demonstrated.
摘要
  1. 报道了用抗真菌药咪康唑治疗26例患血液病和肿瘤的儿童。2. 采用口服或静脉给药的方式进行预防性和治疗性应用。在治疗前、治疗期间和治疗后每周进行一次真菌学检查(粪便、尿液、咽拭子、血液)。3. 总体治疗结果良好,侵袭性真菌病得到预防,已证实的芽生菌感染得到成功治疗。4. 仅1例观察到恶心和呕吐等副作用,未发现造血系统、肝脏和肾脏受损。

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