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结核菌素反应性作为不可切除支气管癌生存时间的预测指标

Tuberculin reactivity as a predictor of survival time in inoperable bronchial carcinoma.

作者信息

Snell N J

出版信息

Thorax. 1979 Aug;34(4):508-11. doi: 10.1136/thx.34.4.508.

Abstract

One hundred and two patients with inoperable bronchial carcinoma who had tuberculin tests at the time of diagnosis were followed up to see if there was any correlation between their degree of tuberculin reactivity and their subsequent survival time. There was a significant difference in survival between positive and negative tuberculin reactors (Log Rank Test P less than 0.05), the former having a median survival time almost twice that of the latter. This did not appear to be related to clinical differences between the groups at the time of testing, and other possible explanations are discussed. Tuberculin testing may be useful in helping to assess prognosis in patients with inoperable bronchial tumours.

摘要

102例无法手术的支气管癌患者在诊断时进行了结核菌素试验,并进行随访,以观察其结核菌素反应程度与随后生存时间之间是否存在任何相关性。结核菌素反应阳性和阴性的患者在生存方面存在显著差异(对数秩检验P<0.05),前者的中位生存时间几乎是后者的两倍。这似乎与检测时两组之间的临床差异无关,并对其他可能的解释进行了讨论。结核菌素试验可能有助于评估无法手术的支气管肿瘤患者的预后。

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Immunologic alterations in bronchogenic cancer. Sequential study.支气管源性癌的免疫改变。序贯研究。
Cancer. 1968 Apr;21(4):623-31. doi: 10.1002/1097-0142(196804)21:4<623::aid-cncr2820210414>3.0.co;2-p.

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