Heilmann H P, Pichlmaier H, Junginger T
Dtsch Med Wochenschr. 1976 Oct 22;101(43):1553-7.
Between 1960 and 1974 a total of 14 937 patients were treated in 16 German surgical departments for bronchial carcinoma. 70% proved to be inoperable. In 30% the tumour was resected, the five-year survival rate of those patients operated on before 1969 being 23%. In suitable cases, lobectomy proved to be a satisfactory radical method of resection in parallel with pneumonectomy, while the operative risk of the latter was twice as high. The operative risk decreased by half during the period of observation. Best results of tumour resection were achieved when in the early stage. The prognosis of anaplastic carcinoma was not significantly worse than that of other histological types. Further improvement in the results of surgical treatment of bronchial carcinoma are to be expected if the operative risk can be decreased further and more patients can be operated on at an earlier stage.
1960年至1974年间,德国16个外科科室共对14937例支气管癌患者进行了治疗。结果显示,70%的患者无法进行手术。30%的患者进行了肿瘤切除,1969年之前接受手术的患者五年生存率为23%。在合适的病例中,肺叶切除术被证明是一种与全肺切除术并行的令人满意的根治性切除方法,而后者的手术风险是前者的两倍。在观察期间,手术风险降低了一半。肿瘤切除的最佳结果是在早期实现的。间变性癌的预后并不比其他组织学类型的预后明显更差。如果手术风险能够进一步降低,并且更多患者能够在更早阶段接受手术,那么支气管癌手术治疗的结果有望进一步改善。