Gullett J, Mills J, Hadley K, Podemski B, Pitts L, Gelber R
Am J Med. 1979 Nov;67(5):891-6. doi: 10.1016/0002-9343(79)90750-2.
A fatal case of disseminated granulomatous infection with a skin lesion and focal encephalitis due to Acanthamoeba astronyxis is reported. Indirect fluorescent antibody tests of both tissue and serum from the patient established the diagnosis. The administration of amphotericin B is ineffective in vitro and has not been effective in vivo. It is recommended that corticosteroid therapy be avoided because it may aggravate the disease. Physicians caring for diseases caused by free-living ameba may call the CDC Parasitic Drug Service.
报告了一例由星状棘阿米巴引起的播散性肉芽肿感染致死病例，伴有皮肤病变和局灶性脑炎。对患者的组织和血清进行间接荧光抗体检测确诊了该病。两性霉素B在体外无效，在体内也未见效。建议避免使用皮质类固醇疗法，因为它可能会加重病情。诊治由自由生活阿米巴引起疾病的医生可致电美国疾病控制与预防中心寄生虫药物服务部。
