Lauder I, Aherne W
Br J Cancer. 1972 Aug;26(4):321-30. doi: 10.1038/bjc.1972.43.
A study of the significance of lymphocytic infiltration was made in a retrospective series of 23 primary neuroblastomata. The degree of lymphocytic infiltration was estimated and scored in 5 categories. Non-parametric rank order statistical methods were used to establish quantitative correlations, particularly with the duration of survival. A significant positive correlation was found both in infancy and childhood. It was found, unexpectedly, that the presence of metastases did not invalidate the correlation between lymphocyte score and survival.
对23例原发性神经母细胞瘤的回顾性系列研究探讨了淋巴细胞浸润的意义。评估淋巴细胞浸润程度并分为5类进行评分。采用非参数等级统计方法建立定量相关性,尤其是与生存时间的相关性。在婴儿期和儿童期均发现显著的正相关。出乎意料的是,发现转移的存在并不影响淋巴细胞评分与生存之间的相关性。