Wüest H P
Arch Int Pharmacodyn Ther. 1979 Jul;240(1):45-52.
The respiratory effects of 1-cis-2-(a-dimethylamino-m-hydroxybenzyl) cyclohexanol-HCl (WY-15,705) were compared to those of pentazocine when given intramuscularly to man. It was found that WY-15,705 was 2.8 times as potent in terms of its respiratory depressant effects.
将1-顺式-2-(α-二甲基氨基间羟基苄基)环己醇盐酸盐(WY - 15,705)与喷他佐辛经肌肉注射给予人体时的呼吸效应进行了比较。结果发现,就呼吸抑制作用而言,WY - 15,705的效力是喷他佐辛的2.8倍。