肥胖小鼠肝脏和肌肉中参与底物循环的酶的最大活性。
The maximum activities of enzymes that are involved in substrate cycles in liver and muscle of obese mice.
作者信息
Newsholme E A, Brand K, Lang J, Stanley J C, Williams T
出版信息
Biochem J. 1979 Aug 15;182(2):621-4. doi: 10.1042/bj1820621.
Abstract
The maximum activities of some dehydrogenases and enzymes involved in substrate cycles are increased in both liver and muscle of obese mice. This suggests that endocrine control rather than maximum capacity of the activities of enzymes constituting such cycles is impaired in obese mice.
摘要
肥胖小鼠肝脏和肌肉中一些参与底物循环的脱氢酶和酶的最大活性均增加。这表明肥胖小鼠中，此类循环的酶活性的内分泌控制而非最大能力受损。
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3
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4
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5
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