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锂盐对人体尿中α-酮戊二酸排泄的影响。

The effect of lithium salts on the urinary excretion of -oxoglutarate in man.

作者信息

Bond P A, Jenner F A, Lee C R, Lenton E, Pollitt R J, Sampson G A

出版信息

Br J Pharmacol. 1972 Sep;46(1):116-23. doi: 10.1111/j.1476-5381.1972.tb06854.x.

Abstract
  1. Lithium ions in therapeutic doses cause an increase in the renal excretion of alpha-oxoglutarate and glutaric acid.2. The excretion is probably due to reduced renal tubular reabsorption.3. Neither citrate, lactate nor pyruvate excretion rises.
摘要
  1. 治疗剂量的锂离子会导致α-酮戊二酸和戊二酸的肾脏排泄增加。2. 这种排泄可能是由于肾小管重吸收减少所致。3. 柠檬酸盐、乳酸盐和丙酮酸盐的排泄均未增加。

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引用本文的文献

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Urinary dicarboxylic acids in patients receiving lithium or rubidium salts.
Psychopharmacology (Berl). 1979 Sep;65(1):85-7. doi: 10.1007/BF00491984.

本文引用的文献

4
RENAL HANDLING OF ALPHA-KETOGLUTARATE BY THE DOG.狗对α-酮戊二酸的肾脏处理
Am J Physiol. 1964 Aug;207:483-94. doi: 10.1152/ajplegacy.1964.207.2.483.

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