Inhibition of neuronal and extraneuronal uptake of noradrenaline by ketamine in the isolated perfused rat heart.
作者信息
Salt P J, Barnes P K, Beswick F J
出版信息
Br J Anaesth. 1979 Sep;51(9):835-8. doi: 10.1093/bja/51.9.835.
PMID:508488
Abstract
The effect of ketamine on the uptake of 3H-noradrenaline in the isolated perfused rat heart was studied. A dose-dependent inhibition of uptake by both neuronal and extraneuronal processes was found. These effects may account for the positive chronotropic and pressor effects of the drug.
摘要
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