药物对肝脏清除吲哚菁绿的刺激作用。
The stimulant effect of drugs on indocyanine green clearance by the liver.
作者信息
Melikian V, Eddy J D, Paton A
出版信息
Gut. 1972 Oct;13(10):755-8. doi: 10.1136/gut.13.10.755.
Abstract
The rate of removal of a standard dose of 25 mg indocyanine green was studied in 67 patients at the bedside using dichromatic ear densitometry. The determination of the percentage disappearance rate per minute and the half life of the dye permitted separation of patients into three groups: those with normal liver function, those with liver damage, and a group taking opiates (9), anticonvulsants (8), phenylbutazone (2), haloperidol (1), and nitrofurantoin (1). The last group showed enhanced clearance of indocyanine green from the circulation.
摘要
采用双色耳密度计在床边对67例患者研究了25毫克标准剂量吲哚菁绿的清除率。通过测定染料每分钟的消失率百分比和半衰期，可将患者分为三组：肝功能正常者、肝损伤患者以及服用阿片类药物（9例）、抗惊厥药（8例）、保泰松（2例）、氟哌啶醇（1例）和呋喃妥因（1例）的一组患者。最后一组患者显示吲哚菁绿从循环中的清除率提高。
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本文引用的文献
1
Use of indocyanine green as a test of liver function.使用吲哚菁绿作为肝功能测试。
Am J Dig Dis. 1963 Mar;8:244-50. doi: 10.1007/BF02232323.
2
Indocyanine green: observations on its physical properties, plasma decay, and hepatic extraction.吲哚菁绿：关于其物理性质、血浆衰变及肝脏摄取的观察
J Clin Invest. 1960 Apr;39(4):592-600. doi: 10.1172/JCI104072.
3
Studies of hepatic function with indocyanine green.用吲哚菁绿进行的肝功能研究。
Gastroenterology. 1960 Dec;39:713-24.
4
5
Hepatic uptake and biliary excretion of indocyanine green in the dog.吲哚菁绿在犬体内的肝脏摄取及胆汁排泄
Proc Soc Exp Biol Med. 1958 Oct;99(1):11-4. doi: 10.3181/00379727-99-24229.
6
A tricarbocyanine dye for continuous recording of dilution curves in whole blood independent of variations in blood oxygen saturation.一种用于连续记录全血稀释曲线且不受血氧饱和度变化影响的三碳菁染料。
Proc Staff Meet Mayo Clin. 1957 Sep 4;32(18):478-84.
7
Indocyanine green clearance as a test for hepatic function. Evaluation by dichromatic ear densitometry.吲哚菁绿清除率作为肝功能检测方法。双色耳密度测定法评估。
JAMA. 1967 Apr 17;200(3):236-40.
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J Pharmacol Exp Ther. 1966 Jun;152(3):509-15.
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