Littleton J M
Drug Alcohol Depend. 1979 Jan-Mar;4(1-2):189-95. doi: 10.1016/0376-8716(79)90066-8.
This paper is intended as a brief commentary on the evidence for adaptation to ethanol at the level of the cell membrane with more detailed consideration of the possible mechanisms for such adaptation. Methodological and conceptual problems are raised and the current views of ethanol tolerance at the membrane level are criticised. The paper includes an abstract of work carried out by the author's group on changes in membrane phospholipid composition of mice during exposure to ethanol by inhalation.
本文旨在对细胞膜水平上乙醇适应性的证据进行简要评论，并更详细地探讨这种适应性的可能机制。文中提出了方法学和概念性问题，并对目前关于细胞膜水平乙醇耐受性的观点进行了批判。本文还包括作者团队关于小鼠吸入乙醇期间膜磷脂组成变化的研究摘要。
