Matsukura N, Kinebuchi M, Kawachi T, Sato S, Sugimura T
Gan. 1979 Aug;70(4):509-13.
Intestinal metaplasia in human stomach was distinguished macroscopically into sucrase-positive and trehalase-positive areas, and sucrase-positive and trehalase-negative areas, by location of these disaccharidase activities with TES-Tape. After location of these two areas with TES-Tape, tissues were taken from them for colorimetric measurement of sucrase, trehalase, leucine aminopeptidase (LAP), and alkaline phosphatase (ALP). Results showed that in the mucosa from sucrase-positive and trehalase-negative areas, trehalase activity was not detectable and the activities of sucrase, LAP, and ALP were lower than in sucrase-positive and trehalase-positive areas.
利用TES试纸通过双糖酶活性的位置，在宏观上将人胃中的肠化生区分为蔗糖酶阳性和海藻糖酶阳性区域，以及蔗糖酶阳性和海藻糖酶阴性区域。用TES试纸确定这两个区域的位置后，从这些区域取材，用于比色法测定蔗糖酶、海藻糖酶、亮氨酸氨肽酶（LAP）和碱性磷酸酶（ALP）。结果显示，在蔗糖酶阳性和海藻糖酶阴性区域的黏膜中，未检测到海藻糖酶活性，且蔗糖酶、LAP和ALP的活性低于蔗糖酶阳性和海藻糖酶阳性区域。
