Kajii T, Ohama K
Hum Genet. 1979 Oct 1;51(2):147-51. doi: 10.1007/BF00287168.
The maternal age distribution of 45,X abortuses was significantly lower than that of chromosomally normal abortuses in two co-ordinated studies. One, carried out in Geneva, included 44 X-monosomic abortuses and the other, in Hiroshima, was based on 38 abortuses with a 45,X karyotype. It was deduced that 45,X conceptuses result from either non-disjunction during paternal meiosis or anaphase lag during meiosis or mitosis, and that anaphase lag is more frequent among young couples than among older ones.
在两项协同研究中，45,X 流产胎儿的母亲年龄分布显著低于染色体正常流产胎儿的母亲年龄分布。一项在日内瓦进行，纳入了44例X单体型流产胎儿；另一项在广岛进行，基于38例核型为45,X的流产胎儿。据推断，45,X 胚胎源自父本减数分裂期间的不分离或减数分裂或有丝分裂期间的后期延迟，并且后期延迟在年轻夫妇中比在年长夫妇中更常见。
