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龋齿:预防前景

Dental caries: prospects for prevention.

作者信息

Scherp H W

出版信息

Science. 1971 Sep 24;173(4003):1199-205. doi: 10.1126/science.173.4003.1199.

Abstract

Combined utilization of measures now available or imminent could reduce caries of the crowns of the teeth to the point of negligibility as a public health problem, if public desire were great enough to motivate changes in some of our habits (64). Universal optimum application of fluoride and substitution of starchy foods for sugary ones (or even simply judicious consumption of sugar) would alone do most of the job. Sealing of susceptible occlusal areas with adhesive polymers promises to protect the sites where fluoride evidently cannot be maximally effective. It seems unlikely that any single measure will be found sufficient to control this multifactorial disease. Consequently, we must continue the search for new means to increase the caries resistance of teeth, to reduce the cariogenicity of foodstuffs, and to check the deleterious activities of cariogenic bacteria. Anticaries food additives and antibacterial agents for intraoral use seem to be approaching practicability. Past performance warrants expectation that ongoing fundamental investigations will produce leads for future development and application.

摘要

如果公众有足够强烈的意愿来推动我们一些习惯的改变,那么综合运用现有的或即将出现的措施,就可以将牙冠龋病减少到可忽略不计的程度,使其不再成为一个公共卫生问题(64)。普遍最佳地应用氟化物,并用含淀粉食物替代含糖食物(或者甚至只是明智地食用糖),这本身就能起到大部分作用。用粘性聚合物封闭易感的咬合面,有望保护那些氟化物显然无法发挥最大功效的部位。似乎不太可能找到任何单一措施足以控制这种多因素疾病。因此,我们必须继续寻找新方法,以增强牙齿的抗龋能力,降低食物的致龋性,并抑制致龋细菌的有害活动。用于口腔的防龋食品添加剂和抗菌剂似乎正接近实用阶段。过去的表现使人们有理由期望,正在进行的基础研究将为未来的发展和应用提供线索。

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