选择性生物转运的动力学。V. 关于红细胞 - 单糖转运系统的更多数据。
The kinetics of selective biological transport. V. Further data on the erythrocyte-monosaccharide transport system.
作者信息
Miller D M
出版信息
Biophys J. 1971 Nov;11(11):915-23. doi: 10.1016/S0006-3495(71)86263-X.
Abstract
Measurements of the rate of loss of sugar from human erythrocytes into sugar-free solutions were made as a function of sugar concentrations. The half-saturation concentration of this process was found to be different from those half-saturation concentrations previously measured by other methods. These data, together with a number of similar data from former publications, are summarized in tabular form and their use in assessing postulated transport mechanisms is illustrated by consideration and rejection of a mechanism in which the transport process is assumed to be the result of a protein conformational change.
摘要
对人体红细胞中糖向无糖溶液流失的速率进行了测量，该速率是糖浓度的函数。发现此过程的半饱和浓度与先前通过其他方法测量的半饱和浓度不同。这些数据，连同以前出版物中的一些类似数据，以表格形式汇总，并通过考虑和否定一种假设的转运机制来说明它们在评估假定转运机制中的用途，在该机制中，转运过程被认为是蛋白质构象变化的结果。
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