Thompson P, Sloman G
Br Med J. 1971 Oct 16;4(5780):136-9. doi: 10.1136/bmj.4.5780.136.
In a group of 339 patients with acute myocardial infarction treated in a coronary care unit, 273 left the unit while improving and were expected to leave hospital alive; 23 had a cardiac arrest or died suddenly while still in hospital-17 died immediately or after temporary resuscitation and six were resuscitated to leave hospital alive. Ventricular fibrillation was found in 13 of the 20 patients attended by the cardiac arrest team. The incidents were scattered from the 4th to the 24th day after the onset of infarction. Risk factors in these "late sudden death" patients were compared with the 250 patients who left the unit while improving and did not die or suffer cardiac arrest. The patients susceptible to late sudden death were characterized early in their hospital course by the findings of severe, predominantly anterior infarction, left ventricular failure, persistent sinus tachycardia, and frequent ventricular arrhythmias. It is suggested that such patients be chosen for prolonged observation in a second-stage coronary care unit.
在一家冠心病监护病房接受治疗的339例急性心肌梗死患者中,273例在病情好转后离开病房,预计可存活出院;23例在住院期间发生心脏骤停或猝死——17例立即死亡或经临时复苏后死亡,6例复苏成功后存活出院。心脏骤停抢救小组救治的20例患者中有13例出现室颤。这些事件发生在梗死发作后的第4天至第24天,呈散发性。将这些“晚期猝死”患者的危险因素与250例病情好转后离开病房、未死亡或未发生心脏骤停的患者进行了比较。易发生晚期猝死的患者在住院早期的特征为严重的、以大面积前壁梗死为主、左心室衰竭、持续性窦性心动过速和频繁的室性心律失常。建议选择这类患者在二级冠心病监护病房进行延长观察。