Bergfors P G
Infection. 1979;7 Suppl 4:S354-8. doi: 10.1007/BF01639013.
There are many difficulties in creating a simple and useful dosage schedule for co-trimazine treatment in children. However, it has been possible to propose a schedule based on age. No advantage can be seen in choosing doses according to weight or other measures of body size. The schedule referred to as schedule B leads to levels of both sulphadiazine and trimethoprim that are as near the optimal as possible with respect to efficacy and side-effects.
为儿童制定简单且实用的复方磺胺甲恶唑治疗剂量方案存在诸多困难。然而，基于年龄制定一个方案是可行的。根据体重或其他身体尺寸指标来选择剂量并无优势。被称为方案B的剂量方案能使磺胺嘧啶和甲氧苄啶的血药浓度在疗效和副作用方面尽可能接近最佳水平。
