• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

L-DOPA treatment in Parkinson's disease: effect on dopamine and related substances in discrete brain regions.

作者信息

Davidson L, Lloyd K, Dankova J, Hornykiewicz O

出版信息

Experientia. 1971 Sep 15;27(9):1048-9. doi: 10.1007/BF02138873.

DOI:10.1007/BF02138873
PMID:5116129
Abstract
摘要

相似文献

1
L-DOPA treatment in Parkinson's disease: effect on dopamine and related substances in discrete brain regions.左旋多巴治疗帕金森病:对不同脑区多巴胺及相关物质的影响。
Experientia. 1971 Sep 15;27(9):1048-9. doi: 10.1007/BF02138873.
2
Effect of L-dopa on brain monoamines and their metabolites in Parkinson's disease.左旋多巴对帕金森病患者脑内单胺及其代谢产物的影响。
Life Sci I. 1971 May 15;10(10):549-57. doi: 10.1016/0024-3205(71)90040-3.
3
Parkinson's disease: from brain homogenate to treatment.帕金森病:从脑匀浆到治疗
Fed Proc. 1973 Feb;32(2):183-90.
4
L-dopa therapy in parkinsonism: mechanism of action.帕金森病的左旋多巴治疗:作用机制
Psychiatr Neurol Neurochir. 1971 Jul-Aug;74(4):331-3.
5
Plasma 3-0-methyldopa in L-dopa therapy of Parkinson's disease.
Mayo Clin Proc. 1972 Jun;47(6):389-95.
6
[Study of dopamine and noradrenaline in the brains of three patients with Parkinson's disease who died in the course of treatment with L-dopa].[三名在左旋多巴治疗过程中死亡的帕金森病患者大脑中多巴胺和去甲肾上腺素的研究]
Rev Neurol (Paris). 1972 Aug;127(2):301-2.
7
On the mode of action of L-dopa in Parkinson's disease.关于左旋多巴在帕金森病中的作用方式。
Biochem Med. 1970 Feb;3(4):321-5. doi: 10.1016/0006-2944(70)90032-3.
8
[Dopa metabolism in relation to the therapy of Parkinson's syndrome].
Actual Pharmacol (Paris). 1971;24:27-49.
9
Biochemical investigations in patients with Parkinson's disease treated with L-dopa.对接受左旋多巴治疗的帕金森病患者进行的生化研究。
Neurology. 1972 Jan;22(1):15-21. doi: 10.1212/wnl.22.1.15.
10
[l-dopa treatment of Parkinson's syndrome and mechanism of action of neuroleptics].[左旋多巴治疗帕金森综合征及抗精神病药物的作用机制]
Med Klin. 1969 Aug 15;64(33):1451-6.

引用本文的文献

1
Dopamine D Agonists: First Potential Treatment for Late-Stage Parkinson's Disease.多巴胺激动剂:晚期帕金森病的首个潜在治疗方法。
Biomolecules. 2023 May 12;13(5):829. doi: 10.3390/biom13050829.
2
D, not D, dopamine receptor activation dramatically improves MPTP-induced parkinsonism unresponsive to levodopa.D,而不是 D,多巴胺受体激动剂显著改善了对左旋多巴无反应的 MPTP 诱导的帕金森病。
Eur J Pharmacol. 2021 Feb 5;892:173760. doi: 10.1016/j.ejphar.2020.173760. Epub 2020 Dec 3.
3
Blood-Brain Barrier and Delivery of Protein and Gene Therapeutics to Brain.

本文引用的文献

1
[The L-3,4-dioxyphenylalanine (DOPA)-effect in Parkinson-akinesia].[左旋多巴(L-3,4-二羟基苯丙氨酸)对帕金森氏症运动不能的作用]
Wien Klin Wochenschr. 1961 Nov 10;73:787-8.
2
[Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system].[去甲肾上腺素和多巴胺(3-羟酪胺)在人脑内的分布及其在锥体外系疾病中的表现]
Klin Wochenschr. 1960 Dec 15;38:1236-9. doi: 10.1007/BF01485901.
3
[Decreased homovanillic acid concentration in the brain in parkinsonian subjects as an expression of a disorder of central dopamine metabolism].
血脑屏障与蛋白质和基因治疗药物向脑内的递送
Front Aging Neurosci. 2020 Jan 10;11:373. doi: 10.3389/fnagi.2019.00373. eCollection 2019.
4
Subcutaneous apomorphine infusion in Parkinson's disease: does it have a role?皮下注射阿扑吗啡治疗帕金森病:它有作用吗?
Postgrad Med J. 1994 May;70(823):344-6. doi: 10.1136/pgmj.70.823.344.
5
Effect of L-dopa on delayed response and visual discrimination in cats and its relation to brain chemistry.左旋多巴对猫延迟反应和视觉辨别能力的影响及其与脑化学的关系。
Exp Brain Res. 1972;15(3):305-17. doi: 10.1007/BF00235914.
6
The effects of 6-hydroxydopamine pretreatment on the accumulation of dopa and dopamine in brain and peripheral organs following L-dopa administration.6-羟基多巴胺预处理对左旋多巴给药后大脑和外周器官中多巴和多巴胺积累的影响。
J Neural Transm. 1972;33(1):63-71. doi: 10.1007/BF01244728.
7
Effect of chronically administered L-dopa on dopa 5HTP decarboxylase and tyrosine and tryptophan hydroxylases in cat brain.长期给予左旋多巴对猫脑内多巴5-羟色胺酸脱羧酶、酪氨酸羟化酶及色氨酸羟化酶的影响。
J Neural Transm. 1973;34(3):171-85. doi: 10.1007/BF01367507.
8
The biochemical evaluation of psychotropic drugs.精神药物的生化评估
Br J Clin Pharmacol. 1976 Feb;3(1 Suppl 1):42-4. doi: 10.1111/j.1365-2125.1976.tb03711.x.
9
Time course of nigrostriatal degeneration in parkinson's disease. A detailed study of influential factors in human brain amine analysis.帕金森病中黑质纹状体变性的时间进程。人脑胺分析中影响因素的详细研究。
J Neural Transm. 1976;38(3-4):277-301. doi: 10.1007/BF01249445.
10
Lisuride, a potent drug in the treatment of muscular rigisity in rats.利苏立得,一种治疗大鼠肌肉强直的强效药物。
Naunyn Schmiedebergs Arch Pharmacol. 1977 Nov;300(2):195-8. doi: 10.1007/BF00505052.
[帕金森病患者大脑中高香草酸浓度降低作为中枢多巴胺代谢紊乱的一种表现]
Klin Wochenschr. 1965 Jul 1;43(13):711-5. doi: 10.1007/BF01707066.
4
Homovanillic acid in different regions of the human brain: attempt at localizing central dopamine fibres.人脑中不同区域的高香草酸:定位中枢多巴胺纤维的尝试。
Brain Res. 1968 Dec;11(3):662-71. doi: 10.1016/0006-8993(68)90154-6.
5
L-Dopa-induced release of cerebral monoamines.左旋多巴诱导的脑单胺释放。
Science. 1970 Oct 2;170(3953):76-7. doi: 10.1126/science.170.3953.76.
6
Aromatic amino acids and modification of parkinsonism.芳香族氨基酸与帕金森病的修饰
N Engl J Med. 1967 Feb 16;276(7):374-9. doi: 10.1056/NEJM196702162760703.
7
Dopamine (3-hydroxytyramine) and brain function.多巴胺(3-羟酪胺)与脑功能。
Pharmacol Rev. 1966 Jun;18(2):925-64.
8
3-O-methyldopa, a new precursor of dopamine.3 - O - 甲基多巴,一种新的多巴胺前体。
Nature. 1971 Apr 23;230(5295):533-4. doi: 10.1038/230533a0.